

Zebra ZD421 4-Inch Desktop Barcode Printer
A 4-inch desktop label printer available in direct thermal, thermal transfer roll and ribbon-cartridge versions, with 203 or 300 dpi and field-installable connectivity.
- Direct thermal, thermal transfer roll and thermal transfer cartridge versions
- 203 dpi standard; 300 dpi optional
- Up to 6 ips at 203 dpi
- 512 MB Flash and 256 MB SDRAM
Zebra ZD421 4-Inch Desktop Barcode Printer overview
The ZD421 is Zebra's mainstream 4-inch desktop printer. It is offered as a direct thermal model, a thermal transfer model using standard 300 m or 74 m ribbon rolls, and a thermal transfer model that uses an easy-load ribbon cartridge. Print speed reaches 6 ips at 203 dpi and 4 ips at 300 dpi.
USB 2.0 and USB host are standard, together with Bluetooth Low Energy for Zebra's setup app and an NFC tag for tap-to-pair. Ethernet, Wi-Fi 5 or Wi-Fi 6 with Bluetooth, and serial can be added, several of them as field-installable modules, so the printer can be adapted after purchase.
An optional battery base lets the printer run away from mains power for a full shift. Zebra lists retail shelf and pharmacy labels, hospitality ticketing and wristbands, healthcare specimen and patient ID labels, government document tracking and logistics shipping labels among its uses.
Key features
- Direct thermal, thermal transfer roll and thermal transfer cartridge versions
- 203 dpi standard; 300 dpi optional
- Up to 6 ips at 203 dpi
- 512 MB Flash and 256 MB SDRAM
- USB 2.0, USB host, BLE 5 and NFC tap-to-pair standard
- Field-installable Ethernet, Wi-Fi with Bluetooth and serial modules
- Optional 2750 mAh battery for cord-free operation
- Accepts 127 mm OD media rolls; roll or fan-fold media
Technical specifications
| Print method | Thermal transfer or direct thermal (by model) |
|---|---|
| Resolution | 203 dpi (8 dots/mm); 300 dpi (12 dots/mm) optional |
| Maximum print width | 4.09 in./104 mm (203 dpi); 4.16 in./106 mm (300 dpi) |
| Maximum print speed | 6 in./152 mm per second (203 dpi); 4 in./102 mm per second (300 dpi) |
| Memory | 512 MB Flash; 256 MB SDRAM |
|---|
| Media width | Direct thermal: 15-108 mm; thermal transfer roll: 15-112 mm; thermal transfer cartridge: 15-118 mm |
|---|---|
| Maximum roll OD | 5.00 in./127 mm |
| Core ID | 0.5 in. and 1.0 in. standard; 1.5, 2.0 and 3.0 in. with optional adapters |
| Media types | Roll or fan-fold, die-cut or continuous, with or without black mark, tag stock, receipt paper, wristbands |
| Ribbon length | 984 ft./300 m or 243 ft./74 m (cartridge: 74 m) |
|---|---|
| Ribbon width | 1.33 in./33.8 mm to 4.3 in./109.2 mm |
| Standard | USB 2.0, USB Host, Bluetooth Low Energy 5 (setup app), NFC tag |
|---|---|
| Optional | Ethernet 10/100; Wi-Fi 5 (802.11ac) with Bluetooth 4.1; Wi-Fi 6 (802.11ax) with Bluetooth 5.3; RS-232 serial (field installable) |
| Battery option | 2750 mAh optional battery |
|---|
| Operating temperature | 4.4 °C to 41 °C |
|---|---|
| Operating humidity | 10% to 90% non-condensing |
| Dimensions | DT: 220.8 x 177.5 x 150.7 mm; TT roll: 267 x 202 x 189 mm; TT cartridge: 254 x 202 x 177 mm |
|---|---|
| Weight | DT: 1.35 kg; TT roll: 2.05 kg; TT cartridge: 2.3 kg |
Specifications are based on the manufacturer’s published information and may change. Please confirm critical requirements with our team before ordering.
Applications & supported media
Applications and industries
Supported media and consumables
- Direct thermal labels and receipt paper
- Thermal transfer ribbons (300 m and 74 m)
- Zebra ribbon cartridges (cartridge model)
- Wristbands and tag stock
Ask us to confirm compatible labels, ribbons or other consumables for your model.
Related solutions
Downloads & datasheets
About Zebra
Zebra Technologies is a US-based manufacturer of enterprise data-capture and printing hardware. Its portfolio spans industrial and desktop thermal barcode printers, mobile printers, card printers, handheld and fixed scanners, rugged Android mobile computers and RFID readers.
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